The Potential of Probiotics from West Sumatra, Indonesia on Low-Density Lipoprotein and Interleukin-6 Levels with Dyslipidemia

Authors

  • Rhinie Uphita Ridwan Nutrition Sciences, Postgraduate programme, Sebelas Maret University, Surakarta, Indonesia
  • Wachid Putranto Faculty of Medicine, Sebelas maret University, Surakarta, Indonesia
  • Adi Magna Patriadi Nuhriwangsa Department of Nutrition, Sebelas Maret University, Surakarta, Indonesia

DOI:

https://doi.org/10.31964/mltj.v10i2.618

Keywords:

Dyslipidemia, interleukin-6, low-density lipoprotein, probiotics

Abstract

Dyslipidemia is a lipid metabolism disorder characterized by abnormal elevations or reductions in one or more lipid fractions within the plasma. This condition is a critical component of both metabolic syndrome and cardiovascular disease (CVD). This study aims to see the potential of curd administration on Low-Density Lipoprotein (LDL) and Interleukin-6 (IL-6) levels in dyslipidemia patients. This study is an experimental study with a pre-post test control group design consisting of a control group and a treatment group totaling 42 people taken randomly at the DR Drs M Hatta Bukittinggi Brain Hospital in June and July 2024. In the three groups, LDL and IL-6 examinations were carried out and measured before and after curd for 14 days. Treatment group 1 was given curd as much as 150 grams, treatment group 2 was given curd as much as 200 grams, given 1x a day, and the control group was not given curd. Data analysis was performed using the Wilcoxon statistical test and paired t-test. Results: There was no significant difference in LDL (p=0.360) and IL-6 (p=0.932) levels after giving curd for 14 days. However, there was a decrease in LDL and IL-6 levels after giving curd for 14 days. Conclusion: The results showed that giving curd for 14 days in the treatment group 1 (150gram) and treatment 2 (200gram) can reduce LDL and IL-6 levels. Consuming probiotics for 14 days can reduce LDL and IL-6 levels.

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Published

2024-12-26

How to Cite

Ridwan, R. U., Putranto, W., & Nuhriwangsa, A. M. P. (2024). The Potential of Probiotics from West Sumatra, Indonesia on Low-Density Lipoprotein and Interleukin-6 Levels with Dyslipidemia. Medical Laboratory Technology Journal, 10(2), 106–115. https://doi.org/10.31964/mltj.v10i2.618

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