Association of the TG/HDL-C and Monocyte Count/HDL-C Ratios with Coronary Artery Disease in Non-ST Segment Elevation Myocardial Infarction
DOI:
https://doi.org/10.31964/mltj.v5i1.207Keywords:
Non-ST segment elevation acute coronary syndrome, Triglyceride/HDL cholesterol ratio, Coronary Artery DiseaseAbstract
Monocyte Count/HDL ratio (MHR) is a simple and inexpensive parameter used as a risk predictor in patients diagnosed with myocardial infarction (MI). This study aims to investigate the association between Triglyceride/HDL-C (TG/HDL-C) ratio and coronary artery disease in patients diagnosed with non-ST segment elevation MI (NSTEMI). Total of 100 patients, 50 patients with NSTEMI and 50 healthy individuals, who had admitted to the cardiology outpatient clinic between January 2018 and January 2019 included in the study. Higher monocyte count, MHR, and TG/HDL-C ratios detected in patients with coronary artery disease in comparison to healthy individuals. Although monocyte count was higher in NSTEMI group, the difference was not statistically significant (p=0.101). There was an increase in the MHR NSTEMI group when compared against the control group (p<0.05). In the NSTEMI group, the best cut-off point for MHR value determined as 2.33 with 56% sensitivity and 76% selectivity. TG/HDL-C ratio was found to be numerically higher in the disease group. However, it was not statistically significant (p=0.386). The best cut-off point for the TG/HDL-C ratio determined as 3.33, with 52% sensitivity and 54% selectivity. In the sub-group analyses performed with regards to coronary anatomy, a statistically significant relation was found between MHR and Circumflex (Cx) artery in predicting the lesion responsible for ischemia (p=0.009). Conclusion In our study, MHR (OR=1.725, p=0.030) was found to be statistically significant in NSTEMI patients, and although TG/HDL-C (OR=1.526, p=0.386) ratio was numerically higher than the control group; it was not statistically significant in predicting severe coronary artery disease.Downloads
Published
How to Cite
Issue
Section
License
Publishing your paper with Medical Laboratory Technology Journal (MLTJ) means that the author or authors retain the copyright in the paper. MLTJ granted an author(s) rights to put the paper onto a website, distribute it to colleagues, give it to students, use it in your thesis etc, even commercially. The author(s) can reuse the figures and tables and other information contained in their paper published by MLTJ in future papers or work without having to ask anyone for permission, provided that the figures, tables or other information that is included in the new paper or work properly references the published paper as the source of the figures, tables or other information, and the new paper or work is not direct at private monetary gain or commercial advantage.
MLTJ journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. This journal is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. This license lets others remix, transform, and build upon the material for any purpose, even commercially. MLTJ journal Open Access articles are distributed under this Creative Commons Attribution-ShareAlike 4.0 International License (CC BY-SA). Articles can be read and shared for All purposes under the following conditions:
BY: You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.SA: If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
